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Spravato® in North Hills, Raleigh

When depression hasn’t lifted, there is another path.

Reviewed by Jonathan Saucier, DNP, PMHNP · Last updated October 19, 2026

Spravato® (esketamine) is an FDA-approved nasal spray for adults with treatment-resistant depression — delivered in a calm, private suite with medical monitoring at every visit.

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FDA-approvedBenefits verified for youPrior authorization handled
Private Spravato treatment suite with a reclining chair
Spravato in-network withAetnaBlue Cross Blue ShieldCignaUnitedHealthcareMedicaid
Is it right for me?

Who is Spravato for?

  • Are an adult living with major depression
  • Have tried antidepressants without enough relief
  • Are looking for an option that works differently from daily pills
  • Can arrange a ride home after each treatment

Spravato is used alongside an oral antidepressant. Your provider will review your history and whether it’s a safe, appropriate fit during a consultation.

Call to schedule a consultation
Clinician reviewing a care plan during a consultation
Your treatment journey

What does Spravato treatment involve?

Consultation & coverage

We confirm Spravato is appropriate, verify your benefits, and submit prior authorization on your behalf.

Treatment sessions

You self-administer the nasal spray under supervision, then relax while we monitor vital signs. You’ll be monitored for at least 2 hours after each dose.

Integration & follow-up

A structured plan helps translate early relief into meaningful, long-term recovery, with ongoing medication management.

Safety first

What happens during a treatment session?

Each session includes pre-treatment preparation, vital-sign monitoring, and post-treatment observation consistent with the Spravato REMS program requirements.

  • Private treatment suite with a reclining chair
  • Dedicated staff support throughout your visit
  • No driving or operating machinery on treatment day, until the next day after restful sleep — plan a ride

Spravato can cause sedation, dissociation, and increased blood pressure, and carries a boxed warning. Your provider will review full safety information with you. Official Spravato information.

Spravato treatment suite at Saucier Psychiatry
Insurance

Does insurance cover Spravato?

We’re in-network for Spravato with the plans below and handle benefits verification and prior authorization.

PlanSpravato in-network
AetnaYes
Blue Cross Blue ShieldYes
CignaYes
UnitedHealthcareYes
MedicaidYes

Coverage depends on your specific plan and prior authorization approval. Coverage varies by plan; call (910) 273-7572 to confirm your benefits. Don’t see your plan? Call us — we’ll talk through options. See all plans on our insurance page.

Safety

Important Safety Information

WARNING: SEDATION; DISSOCIATION; RESPIRATORY DEPRESSION; ABUSE AND MISUSE; and SUICIDAL THOUGHTS AND BEHAVIORS

  • Sedation, dissociation and respiratory depression: Spravato can cause sleepiness, dissociative effects (feeling disconnected from yourself, your thoughts, feelings and surroundings) and slowed or shallow breathing. Patients are monitored by a healthcare provider for at least 2 hours after each dose.
  • Abuse and misuse: Spravato contains esketamine, a controlled substance (CIII), and may be misused. Your provider will check for signs of abuse and misuse.
  • Suicidal thoughts and behaviors: Antidepressants may increase suicidal thoughts and behaviors in people 24 years and younger. Spravato is not approved for children. Call your provider right away if depression worsens or you have new or worsening suicidal thoughts.

Spravato is available only through a restricted program, the Spravato REMS, and is given only in a certified healthcare setting. You use the nasal spray yourself under the supervision of a healthcare provider and do not take it home.

Spravato may also raise blood pressure and can affect attention, judgment and thinking. Do not drive or operate machinery until the next day after a restful sleep. Tell your provider if you are pregnant, planning to become pregnant or breastfeeding. Common side effects include dissociation, dizziness, nausea, sedation, vertigo, decreased sense of touch, anxiety, lethargy, increased blood pressure, vomiting and feeling drunk.

Individual results vary. This is not the complete safety information. See the full Prescribing Information, including the Boxed Warning, and Medication Guide. If you are in crisis, call or text 988.

Spravato FAQ

What do patients ask about Spravato?

What is Spravato?
Spravato® (esketamine) is an FDA-approved nasal spray used to treat adults with depression that hasn’t improved with traditional medications. It works differently than standard antidepressants and is administered in-office under medical supervision.
Who is Spravato for?
Spravato may be a good option for adults who have tried antidepressants without enough relief and are experiencing treatment-resistant depression. We’ll help determine if it’s the right fit during your consultation.
How is it different from antidepressants?
Most antidepressants are taken daily and can take weeks to work. Spravato works differently in the brain and may help reduce symptoms more quickly for some patients.
What happens during a session?
You’ll relax in a comfortable, private setting in our North Hills office. Spravato is self-administered as a nasal spray under the supervision of your provider, and you’ll stay with us for monitoring afterward to ensure your safety and comfort.
How long does each appointment take?
Plan for at least 2 hours in the office. Under the Spravato REMS program, you’re monitored by our staff for at least 2 hours after each dose, until you’re ready to leave. Arrange a ride home: you can’t drive or operate machinery on treatment day, until the next day after a restful sleep.
Can I drive myself home?
No. Per the FDA label, you should not drive or operate machinery until the next day after a restful sleep, so please arrange a ride home after every treatment.
Does insurance cover Spravato?
Many plans cover Spravato. We’re in-network for Spravato with Aetna, Blue Cross Blue Shield, Cigna, UnitedHealthcare, and Medicaid. Coverage varies by plan; call (910) 273-7572 to confirm your benefits. Our team verifies your benefits and handles prior authorization.
Referring a patient for Spravato? Fax referrals to (984) 220-9351 or visit our referring providers page. We aim to call your patient within one business day.
Take the first step

Is Spravato right for you?

Call to schedule a consultation — we’ll verify your benefits and handle prior authorization.

Call (910) 273-7572Request a callback